Pengaruh Variasi Konsentrasi Jojoba Beads terhadap Stabilitas, Efektivitas Eksfoliasi, dan Aktivitas Antioksidan Lulur Ekstrak Daun Sirsak (Annona muricata L.)
DOI:
https://doi.org/10.57218/jkj.Vol5.Iss3.3012Kata Kunci:
aktivitas antioksidan, daun sirsak, eksfoliasi, jojoba beads, lulur herbaAbstrak
Lulur merupakan sediaan kosmetik yang berfungsi mengangkat sel kulit mati dan membantu menjaga kesehatan kulit. Ekstrak daun sirsak (Annona muricata L.) sebagai sumber senyawa antioksidan dan jojoba beads sebagai eksfoliator alami berpotensi menghasilkan sediaan kosmetik multifungsi. Penelitian ini bertujuan mengetahui pengaruh variasi konsentrasi jojoba beads terhadap karakteristik fisik, stabilitas, efektivitas eksfoliasi, dan aktivitas antioksidan lulur ekstrak daun sirsak. Penelitian dilakukan secara eksperimental laboratorium dengan memformulasikan lulur tipe minyak dalam air yang mengandung ekstrak daun sirsak 1,5% dan jojoba beads 4%, 6%, dan 8%. Evaluasi meliputi organoleptik, homogenitas, pH, viskositas, daya sebar, stabilitas enam siklus heating–cooling, iritasi menggunakan HET-CAM, efektivitas eksfoliasi menggunakan metode gravimetri tape stripping, serta aktivitas antioksidan menggunakan metode DPPH. Pengujian karakteristik fisik dan aktivitas antioksidan dilakukan tiga kali replikasi (n = 3), dengan hasil dinyatakan sebagai rerata ± standar deviasi. Ekstrak daun sirsak menunjukkan aktivitas antioksidan kuat dengan nilai IC₅₀ sebesar 27,22 ± 1,14 ppm. Uji eksfoliasi pada 34 subjek menunjukkan perbedaan signifikan antara kontrol dan formula yang mengandung jojoba beads (Z = −5,086; p < 0,001), dengan seluruh subjek menunjukkan peningkatan nilai eksfoliasi. Sebelum stabilitas, F3 dengan jojoba beads 8% memiliki inhibisi tertinggi sebesar 61,05%, kemudian menurun menjadi 41,96% setelah stabilitas. F1 dan F2 mengalami perubahan homogenitas setelah stabilitas. Formula F3 berpotensi dikembangkan sebagai lulur herbal dengan aktivitas eksfoliasi dan antioksidan.
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